Leiomyosarcoma

Leiomyosarcoma is a rare malignant tumor that develops from smooth muscle cells. It can occur in any organ containing smooth muscle, most commonly the uterus, gastrointestinal tract, soft tissue and blood vessels.

Leiomyosarcoma is characterized by infiltrative growth and the ability to give distant metastases. Clinical manifestations depend on the location of the tumor. Often the first symptom is the appearance of a tumor-like formation. Pain syndrome and organ dysfunction develop when the tumor size is significant.

The diagnosis of leiomyosarcoma is established on the basis of histological examination. Treatment includes surgical removal of the tumor, radiation therapy, and chemotherapy. The prognosis depends on the size and stage of the tumor process, usually less favorable than for benign tumors of smooth muscle tissue.

Leiomyosarcomas are neoplasias that arise from smooth muscle cells that form the basis of the inner lining of organs such as the uterus, lungs, gallbladder or esophagus. They usually develop as a result of an imbalance between prolentic and anti-iatic signals.

Development