Porokeratosis Palmoplantar Papillary

Palmoplantar papillary porokeratosis: causes, symptoms and treatment

Palmar-plantar papillary porokeratosis (porokeratosis papillomatosa palmaris et plantaris) is a rare genetic skin disease that manifests itself in the form of papillomas and horny formations on the feet and palms. Porokeratosis palmoplantar papillary is inherited according to the principle of autosomal dominant type, that is, the disease manifests itself in people who have only one defective gene.

Palmoplantar papillary porokeratosis can occur at any age, but most often the disease is diagnosed in people aged 20 to 40 years. The main symptom of the disease is papillomas and horny formations on the feet and palms, which can be painful and cause discomfort when walking.

The cause of palmoplantar papillary porokeratosis is considered to be a mutation of the gene responsible for the synthesis of the enzyme necessary to create healthy skin. This leads to disruption of the process of skin keratinization and the formation of papillomas and horny formations.

To diagnose palmoplantar papillary porokeratosis, microscopy and biopsy of skin lesions are used. Treatment of the disease is aimed at reducing symptoms and improving the quality of life of patients. For this purpose, keratolytic agents, cryotherapy (cold treatment), laser therapy and surgical removal of skin lesions can be used.

Although palmoplantar papillary porokeratosis is a rare disease, it is important to consult a doctor if any changes appear on the skin of the feet and palms. Early contact with a specialist can help prevent the development of complications and improve the prognosis of the disease.