Relman-Hun-Salus Symptom

Relmon-Hunn-Salles syndrome is a rare hereditary eye disease that manifests as “flying” opacities in the vitreous humor (vitreous corpus fibrous membrane). The disease was first described by Eric Salles in 1875 and later renamed in his honor. In 1948, Janos Gunning described several cases where the patient's condition "fluctuated" in which symptoms came and went, similar to a mercury ball or fluorite device. Rolf Kirnberger and Iddo M. Relman later isolated and described the syndrome in 1965 after analyzing cases described by Gunning. They gave it the name "Kirnberg-Rellman phenomenon" and defined it as hereditary parosmia. The first patients were described in various European countries, mainly in Germany and Switzerland. It was found that some members of families of different backgrounds and ethnicities suffered from the syndrome. Relman-Kirnberg-Sallier syndrome has been classified as a rare form of Hatcher's disease, one of the rare inherited diseases of the retina.

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