Retinopathy Angiospastic Central

Retinopathy angiospastic central (RASC) is a pathology of the fundus of the eye, accompanied by the proliferation of newly formed vessels, dilation of retinal vessels, the development of ischemia, choroidal neovascularization or peripapillary necrosis. Characteristic changes in blood vessels begin with the appearance of multiple small pinpoint hemorrhages on the retina, which merge into one area of ​​proliferation. The nature of the blood flow also changes: pulsating and static-dynamic retropulsions often occur, reducing perfusion rates and leading to hypoxia (ischemia) of the retina.

First, the process is reversible; regression of vascular changes is possible during treatment of the underlying disease. In the case of a stable form of the disease, due to the development of detrusions and lacunar avascular zones, late stages of the course are formed, during which characteristic changes in the optic discs and central visual field occur. They indicate the progression of the pathological process. There is flattening of the excavation, apoptosis of neurons in the ganglion layer, detachment of the neuropil and diffuse atrophy of the optic nerve.

The basis of disease prevention is a healthy lifestyle, balanced nutrition, and dosed physical activity. It is necessary to control blood pressure and monitor weight. Patients should have a comprehensive approach to treatment. Anticoagulants (if there are bleeding disorders) and antihypertensive drugs are used. It is recommended to adhere to anti-atherosclerotic measures. Vasodilators and antiplatelet agents are prescribed. Gels and drops that have angioprotective and antihypoxia are used locally.

According to WHO, about 80% of cases of chronic arterial hypertension in developed countries are associated with the presence of arterial hypertension (AH). Unlike the health care situation in most countries of the world, in Russia hypertension is the main problem in the epidemiology of cardiovascular diseases. So, according to the Ministry of Health

Angiospastic central retinopathy is a rare autosomal recessive disease that occurs due to hereditary defects in the gene encoding endocytosis of intravascular mucopolysaccharidase-1-epidermal lyse (lysosomal alpha-L-iduronidase, LAI); it is characterized by a progressive binocular stereoscopic worsening panorama of the visual field of the peripheral part of the fundus, but the binocularity and stereoscopic nature of the lesion picture corresponds to no more than only half of the patients. It happens