Introduction
Aging is a natural process that occurs in all living organisms, including humans. Physiological old age is associated with changes and limitations in the functioning of various organs and systems of the body, which leads to a decrease in their performance and an increased risk of developing various diseases. In this article, we will look at the general concepts of physiological aging and its consequences, as well as effective strategies to combat it.
Physiological aging and its mechanisms
According to molecular clock theory, physiological aging is associated with the accumulation of damage in cells, which accelerates as time passes by in the body. As cells age, they become less resistant to damaging factors such as ultraviolet rays, free radicals, oxidative stress, glucose-insulin resistance and other factors. Additionally, deficiencies in hormones, neurotransmitters, and other biological substances may also contribute to aging.
The main paths of physiological aging
In the process of physiological aging, the following main pathways can be distinguished:
Tissue aging Muscle fibers lose their elasticity, become stiff and unable to quickly contract and relax. This causes a decrease in muscle strength and endurance. Skeletal bones become brittle and bone density decreases (osteoporosis).
Metabolic aging Under the influence of hormones, the level of growth hormones and insulin decreases, which is a major factor in senile dementia (cognitive decline), weight loss and appetite. The level of adrenaline also decreases sharply and