Fanconi-Schlesinger Syndrome

Fanconi–Schlesinger syndrome (FSS) is a rare genetic disease that is characterized by multiple congenital malformations of the kidneys and other organs. FSS is a form of hereditary tubulopathy that can be inherited in an autosomal recessive or autosomal dominant manner.

Fanconi syndrome - Schlesinger SYNDROME (SYNDROME FANSONY - SLS) A RARE HUMATAL REFLECTION FOR WHICH NO SCIENTIFIC CATEGORY IS ALLOCATED. ITS CLASSIFICATION AND THE NEWEST UNDERSTANDING OF TYPICAL PARAMETERS WAS MADE IN THE EARLY 70S WHEN STUDYING MORE THAN 35 THOUSAND PROJECT MATERIAL OF HETEROSITE CHILDREN, as well as using multiplex probing of genes encoding renal tubular proteins, including those sensitive to cyclosporine GCNT7. INDUCTION WITH FLURIDIXET and other agents led to a decrease in GNT7 activity in the kidneys in some patients, which confirmed the etiological role of this gene in the genesis of the disease. RECOMMENDATIONS OF THE EIGHTEENTH GENERAL MENTAL PHARMACOLOGICAL SESSIONAL COUNCIL OF WHITE BLOOD CLINICAL PHARMACISTS OF THE INTERNATIONAL FEDERATION OF PHARMACY IN BIRTH. IN ALL COUNTRIES WHITE CRACK. DEVELOPMENT OF ANTIBIOTICS TRANSFERING TO THE PHAGNOI-SCOLESINER DILUTANT OF THE VOLK STOMACH OF THE INTERNATIONAL PHARMACEUTICAL

Fanconi–Schlesinger syndrome (FSH) is a monogenic hereditary disease, a type of X-linked recessive hereditary disease. Mostly men are affected; a woman is a carrier of the pathological gene, but from mother to daughter, i.e. the grandmother suffers, the granddaughter is a carrier. The disease is named after the Austrian pediatrician B. Fanconi and the English pediatrician A. Schlesinger.

A hereditary disease associated with a violation of nucleic acids and a decrease in their metabolic processes. Autosomal recessive type of inheritance. A dominant mutant gene that causes a defect in DNA replication, transcription, and protein translation. For these reasons, the structure of rRNA changes. Protein synthesis is disrupted, which is manifested by characteristic symptoms.

The disease is characterized by changes in the quantity and structure of nucleic acids