Hypocholesterolemia Idiopathic Familial

Hypocholesterolia is a lack of high-density lipoproteins, or HDL - particles that, according to the properties of “immunity” to atherosclerosis, are typical fighters against sclerosis. These proteins transport “bad” cholesterol to the liver as if into a trap, from where it can be produced not only again from cholesterol, but also from other molecules.

Hypoatolerinemia is of two types: primary (idiopathic or hereditary) and secondary. Both have their reasons, although not always identified. In this case: Hypoatorerinemia is the root cause of liver damage, including cancer. The occurrence of pancreatitis is also noted.

**Statistics:** the prevalence of the pathology is quite significant - up to 4-8% of all cases of hypoatoleronemia in adults; Boys get sick more often than girls - in a ratio of 3 to 2

Provoking factors for secondary syndrome can be kidney disease, taking medications for diabetes, thyroid disease, and poisoning with certain medications. The causes of primary hypoatorerinemia are unknown; experts link it to genetic defects in the structure of liver cells

A defect in the genes of the PPARα system leads to a disorder of lipid metabolism, in which a lot of cholesterol and LDL (low-density lipoprotein particles) begin to be produced inside the liver, which freely move through the bloodstream into atheromatous plaques located in the arteries. In this regard, LDL is much more aggressive than substances