Page Syndrome

Page syndrome: causes and features of the course of the disease.

Page (Pages) syndrome is a rare neurological disease that is associated with damage to the neuromuscular system. The syndrome can also be combined with a decrease in nerve sensitivity. The cause of the syndrome is said to be a mutation in the GTP-cyclohydrolase 1 gene. This disease was first described by the American physician James Page. Page syndrome mainly occurs in men. The disease is hereditary. The first manifestations of the disease appear between the ages of 3 and 9 years. In the case where Page syndrome is suspected in a patient, it is necessary to involve a neurologist, endocrinologist, geneticist, and immunologist in the examination. Diagnosis of Pages syndrome can begin during the pregnancy of the child, so