Beignet-Tennesson Chill Lupus

**Beignets-Tennessen, or Lupus Chill**

_Date of accession:_ January 1, 1939

This is a rare chronic skin disease, which is characterized by periodic exacerbations in the form of attacks of itching, fever and painful rashes - the so-called Besnier-Tennessen blisters - followed by independent healing. Mostly men of working age suffer from polyneuropathy syndrome. The untreated process continues for 2–3 years or more.

Short-term attacks of the disease in most cases do not cause severe stress in patients, but due to impaired skin function, patients cannot work regularly, so they are assigned disability group I. They develop a characteristic behavioral stereotype in which patients avoid touching their hands. The exacerbation period lasts 6–8 months. Remission can vary in duration - from several months to 5-7 years (its duration does not depend on the effectiveness of treatment).

The cause of the disease is disorders of the autonomic nervous system with a predominance of sympathicotonia. The role of herpes simplex virus type II, type 6 and other viruses has been established. Histological examination of the affected skin reveals foci of the proliferative phase of inflammation, which contain a significant number of lymphocytes and histiocytes, and sometimes mast cells. The epidermis is swollen, the capillaries are dilated, and small hemorrhages are located next to them.

In the origin of pathological changes in lupus, the role of microcirculation disorders associated with rheumatoid changes in the connective tissue of the dermis, impaired immunological reactivity of the body, as well as activation of cells of the mononuclear phagocytic system has been established. Characteristic signs of vascular spasm and microcirculation disorders. In the vessels of the skin, changes in the cellular composition of the wall are clearly expressed with a sharp development of precapillary anastomoses between small arterioles, arteriolar stasis and venous plethora. There is an increase in the permeability of the vascular walls and an increase in the number of resorbing capillaries. The blood coagulation system is activated, that is, the number of platelets increases, prothrombin time increases, and fibrinolytic properties decrease. The rheological properties of blood are changed. Microcirculation is also disrupted in the innervation neurovascular bundles extending from the nodal elements to the head of the hair follicles. The utilization of oxygen and energy resources by tissues decreases, the secretion of lysosomal enzymes increases, in addition, altered sebaceous glands rise above the cortex. In turn, there is a suppression of the activity of odontogenic facial nerves and the general licking reflex. Immune complex pathology is characterized by the presence of immunoglobulins of classes A and M (more than M), with a decrease in the total amount of immunoglobulin A in the blood serum and a sharp deficiency in the skin, fibrotic processes in tissues are significantly activated. The latter is regarded as a consequence of pronounced spasm of smooth muscle cells of skin vessels with a further increase in vascular permeability

Beignet-Tennesson Lupus pernio is a skin disease that occurs due to infection with Staphylococcus aureus. It appears on the torso, neck and face and may be accompanied by high fever, pain and redness of the affected area. In the article we will tell you how the disease manifests itself, what symptoms and treatment methods exist, as well as what needs to be done to prevent the disease.

This disease was first described in the 19th century by the French dermatologist E. Besnier (1825-1897) and his colleague N. Tennisson (1861-1843), later this disease was called Besnier-Tennesson chills. Symptoms of Beignet-Tennesson fever are characterized by the following manifestations: - skin manifestations have high body temperature and itching; - the affected area has a characteristic reddish-brown color, which gradually develops into a purple color; - in the center of the affected area there is a pimply protrusion; - a ring-shaped depression develops around the protrusion; - a reddish-violet coating is visible above the surface of the skin.