Birmera Symptom

Birmera syndrome (syn.: Bermera syndrome) is a syndrome of excessive growth of the gastric mucosa in stomach cancer. The term "s. B. (B.-sin)” was proposed by E.F. Peterson in 1950 as a synonym for the old term “Gastric apepsia syndrome” in order to remove unfounded criticism against surgeons for supposedly meaningless resection in the absence of pain.

A detailed synonym for the name of the syndrome is “syndrome of increased gastric secretion due to an increase in the volume of the gland” (Sukhareva L. M. et al., 1994, 2004).

The main manifestation of Biermer syndrome is the appearance of gastrostasis. In the stomach cavity there is a continuous rejection of mucus, as evidenced by the appearance of a large amount of gastric contents. Characteristics of mucus rejection are pain in the epigastric region, as well as dyspeptic disorders that appear episodically (“hidden” pain and a “periodic” picture of the disease, according to E. D. Lappo, N. G. Tsitov). These phenomena are very reminiscent of the manifestations of the gastritis form of peptic ulcer disease (chronic catarrhal gastritis, NERD), which occurs with pronounced gastroparesis in the phase of gastritic gastritis, but without connection with stress.

The second pathognomonic symptom of Biermer syndrome is the presence of a cancerous tumor of the stomach or other localization, which “triggers” the chronic process of hyperplasia of the mucous membrane. A biopsy reveals atypical cells with signs of atypia and pronounced vascular changes. Hyperplasia is quite extensive, reaching significant sizes due to the irregular shape of glandular cells (hyperplastic gastritis). Usually, a large amount of detritus is observed in the gastric contents, which, in combination with increased secretions, facilitates the existence of constant peristaltic stomach disorders due to the constant reflux of contents from the duodenum