Hyperostosis Systemic Diaphyseal Congenital

Hyperostotic systemic diphyseal congenital osteopathy is a rare, genetically inherited skeletal disorder that can present with a variety of symptoms, including pain, stiffness, and limited movement.

Causes of Hyperostosis can be hereditary or acquired. They are caused by metabolic disorders leading to



Systemic diaphyseal hyperostosis congenital (HSDH; hypertrophy of the process of calcification in the epiphysis; HIPEC) is a genetically inherited disease of the skeletal bones, characterized by pathological calcification in any epiphyses in humans or animals during fetal development, born with systemic signs,



**Congenital systemic diaphysial hyperostosis** [1][2] (Fokker syndrome[3], Gunther syndrome[4]; other names: - hyperophic bone disease[5], hyperphysia of the 8th and 9th thoracic bones and lumbar vertebrae, hyperosclerosis of the hip joint[6], systemic skelematosis[7]) is a hereditary disease characterized by the absence of ossification of the bodies at an early age