Kalera Disease

Kalera Disease: symptoms, causes and treatment

Kalera disease is a rare cancer that was described by the Austrian physician Otto Kaler at the end of the 19th century. This disease mainly affects bone tissue, causing bone destruction and metabolic disorders.

Symptoms of Kalera disease may include bone pain that is worse at night, fatigue, weight loss, increased bleeding, and a tendency to break bones. In some cases, kidney dysfunction, increased fatigue, and even cardiac dysfunction may occur.

The causes of kalera disease are unknown, but it is believed that genetic factors may play a role in the development of this disease. Kalera disease most often occurs in older people, but can also occur in younger people.

Various methods are used to diagnose Kalera disease, such as X-rays, computed tomography, magnetic resonance imaging and biopsy.

Treatment for Kalera disease depends on the stage and severity of the disease. In some cases, chemotherapy, radiation therapy, and bone marrow transplantation may be used. It is important to note that calera disease does not have a complete cure, but there are many treatments and supportive care that can improve a patient's quality of life.

In conclusion, calera disease is a rare but dangerous disease that requires professional medical intervention. If you notice the symptoms described above, consult your doctor for diagnosis and treatment. It is important to know that early consultation with a doctor can significantly improve the prognosis and quality of life for this disease.



*Kalera Disease* is a very rare disease that is characterized by lung damage and the development of multiple organ failure. The name of the disease comes from the name of the Austro-American physician and therapist Oscar Kahler (December 21, 1853 - August 4, 1892), who was one of its first known descriptors. Today, the disease does not have a specific name used to identify it, but it is included in the list of the world's rarest diseases, which are defined as disorders that are significant, complex, rare, and have a consistent spread throughout the world's population for unknown reasons. According to the medical scientific literature of recent years, the prevalence of diseases depends on gender (the concentration of diseases in men and women). In 75% of cases it is detected in women.

**Difficulties in identifying the disease**

The first information about the disease was described by O. Kahler in 1881 as cases of tuberculosis in several patients suffering from hemoptysis. In his work, the doctor noted an unusually accelerated course of the tuberculosis process with the exclusion of all factors simulating the onset of the disease. He diagnosed it based on blood tests, the detection of atypical cells in the sputum and pronounced changes in the composition of formed elements and blood cells. This was important because the first signs of the disease often did not correspond to the presence of tuberculosis forms. In one of the patients, at a certain point in the development of signs of the disease, remission was even detected through treatment. The diagnosis of Kalera disease is confirmed by the following clinical signs: - Cyanosis of the upper half of the body, especially the veins visible on it. - Maculopapular spots or redness on the skin - Latin lymphadenopathy - Hyperthermia difficult to control with conventional means (intravenous therapy may be required) - Dry or nonproductive cough. - Vomiting Symptoms Ka