Looser-Milkman Disease

Looser-Milkman disease: symptoms, causes and treatment

Looser-Milkman disease, also known as osteomalacia or soft bone syndrome, is a rare disease characterized by decreased bone mineral density and softening of bone tissue, leading to deformation and brittleness.

Named after the two radiologists, Walter Looser and Louis Milkman, who first described the disease in the early 20th century, Looser-Milkman disease is most common in women over 50 years of age.

The cause of the development of the disease is insufficient intake of calcium, phosphorus and vitamin D into the body, which are important components for the formation of bone tissue. Also, the risk of developing Looser-Milkman disease increases with diseases of the kidneys, liver, thyroid gland, as well as with certain nutritional disorders and hormonal disorders.

The main symptoms of Looser-Milkman disease are bone pain, skeletal deformities, susceptibility to fractures, muscle weakness and decreased height. In more severe cases, dental problems, growth retardation in children, and cardiovascular problems may occur.

To diagnose Looser-Milkman disease, X-rays are used to assess bone density and detect softening.

Treatment of Looser-Milkman disease is aimed at eliminating the deficiency of calcium, phosphorus and vitamin D in the body. In mild cases, it is sufficient to increase the consumption of foods rich in calcium and phosphorus, as well as a course of vitamin therapy. In more severe cases, it may be necessary to prescribe medications that improve the metabolism of calcium and phosphorus in the body.

Another important aspect of treatment is adjusting the patient’s diet and lifestyle, including moderate physical activity, quitting smoking and limiting alcohol consumption.

In conclusion, Looser-Milkman disease is a rare but serious condition that can lead to skeletal deformities and increased bone fragility. However, thanks to timely diagnosis and comprehensive treatment, it is possible to improve the patient’s condition and prevent the development of complications.

Loozerov-Milkman disease is a systemic connective tissue disease primarily affecting the heart, occurring with fever, peritoneal effusions, and hemorrhagic syndrome. At L.-M. b. polyarthritis of small joints of the hands and impaired immunity are noted. It manifests itself in a paroxysmal course, simulating a viral infection or sepsis in children and acute rheumatoid arthritis in adults (with fever, pain in the joints and abdomen, colitis, etc.). Similar symptoms are also observed in acute hemolytic uremia, burn disease, and some orphan diseases (for example, chronic yersiniosis, Wegner's granulomatosis). It has been established that the disease

Loozer-Milkman disease is a form of chronic infectious disease that develops as a result of human infection with certain microorganisms. It manifests itself with different symptoms and in different age groups of the population.

The name of the disease was first proposed in 1995 by Russian surgeon N. Yu. Borodulin. The disease has a rather confusing etiology, which has not been established to date.

Forms of manifestation. Loozerovo-Milkmenovskaya (synonyms: KBMK, HIVIMS or LMB) is a chronic infectious disease with a progressive course. For this type of disease