Lupus Erythematosus Vegetative

Lupus is a skin disease of allergic origin. A distinctive feature of lupus vegetans erythematosus and systemic lupus erythematosus is the deposition of antibodies in the blood that interact with the surface of the skin, which leads to the development of various symptoms in the skin. In typical cases, the development of the disease begins between the ages of twenty and forty years. Foci of inflammation are localized on the extensor surfaces of the extremities (forearms, shoulders, and less commonly in the buttocks). These changes resemble “pseudoallergic” edema - against the background of normal pink skin, extensive or limited focal painful redness, peeling, and pseudoatrophic scars (flaccid) appear. Sometimes foci of inflammation are located on the face (nose, cheeks), less often on the torso. Their localization is determined by the condition of the skin, age-related characteristics of blood supply and innervation. Vegetative lupus erythematosus. Symptoms develop gradually over several weeks or months, and the symptoms of an infectious disease with a characteristic tendency to self-healing become prevalent. Often, lesions on the skin undergo suppuration with secondary rub

Lupus erythematosus is a rare dermatological disease. It is one of the cystic angiofibroproliferative skin lesions.

It is represented by papules and plaques with hemorrhagic contents of various shapes and sizes, prone to peripheral growth, central scarring and peripheral atrophy. There is a predominant localization of rashes on the skin of the face with the development of deformation due to frequent friction and traumatization of the rashes. At the same time, there is a clinical form in which the rashes are predominantly localized on the scalp, chest, back, but the face can also be involved in the process. The rapid development of the process after exposure to mechanical, physical, chemical factors and electromagnetic field waves, especially low frequencies, is characteristic, which indicates the importance of allergic and autoimmune mechanisms in the pathogenesis. As a result of specific damage to the lymphatic vessels, the development of arteriosclerotic and varicose changes in the vessels with dilation and obliteration is observed. Immune inflammation is considered an important pathogenetic mechanism of damage to internal organs (heart, liver, brain, lungs). Currently, cases of a hereditary nature with a family burden have been described. Most patients suffering from lupus erythematosus are between 50 and 60 years of age. Women get sick more often than men. The exact cause of this disease has not been identified. The disease begins with the spontaneous appearance of persistent hyperemia of the skin on the face and flexor surface of the limbs. In half of the patients the disease is accompanied by itching. The mucous membranes of the eye, ear, mouth, and vagina are rarely affected. Star-shaped brown-red spots with a diameter of 3 to 4 cm appear, which, merging, form plaques of various shapes. However, there are mild forms of damage when plaques are not observed. This gives grounds to use the term “smoothed lupus erythematosus” or “lupus without plaques” in such cases. External manifestations of the disease are short-term, characterized by slight persistence and polymorphism of the course. After a few days, the spots begin to resolve through gray-white nodules, the diameter of which reaches 2–3 cm. Normal skin remains in place of the spots, and scars form in the nodules. The process lasts from several days to a month. If the disease has a long course, the lesion can acquire the features of a developmental defect. Along with external manifestations of the disease, internal organs are affected. The disease is accompanied by general fatigue, headaches, hyperkeratosis of the palms and soles. Sometimes myalgia, oliguria, arthralgia, and low-grade fever occur. On average, the disease lasts 5 years and ends with spontaneous recovery. The disease often becomes chronic, which many years. Treatment is aimed at eliminating itching, eliminating skin lesions and preventing damage to internal organs. The prognosis can be favorable if the correct treatment is used. In affected areas, it is possible to restore normal functioning of the skin. It is important to protect the skin from injury, hypothermia and overheating. Keratoplasty preparations should be used locally at the stage of damage and after it. During clinical manifestations of the disease, antibiotics, vitamins B, B,

**Lupus vegetans, Hailey-Heileen lupus, annular lupus** is a systemic connective tissue disease of unknown etiology, primarily affecting the skin and manifesting itself in characteristic rashes called “lupus plaques.” In the international classification of diseases, 1st revision ICD-1 (International Statistical Classification of Diseases and Related Health Problems), lupus belongs to class XIII - other rheumatic diseases. In addition, to describe the pathological condition called “lupus erythematosus”, separate headings (sections) have been introduced in the ICD: L93.0 - idiopathic, L93.- - unspecified and L94.0 - systemic. Despite the complex logic of dividing incidence, the use of both approaches makes it possible to very accurately estimate the prevalence of lupus in the country and in the world.