Barr Chromatin Body

Chromosomes are the genetic material that contains information about our heredity. Humans usually have 46 chromosomes, divided into 23 pairs. Each pair consists of one chromosome received from the mother and one chromosome received from the father. However, women have one extra chromosome - the X chromosome.

Men have one X chromosome and one Y chromosome. When a sperm fertilizes an egg, it produces a zygote containing 46 chromosomes, including one X chromosome from the mother and one X or Y chromosome from the father. Thus, the sex of the child depends on which chromosome the sperm contains - X or Y.

However, women have two X chromosomes, which means one of them is not needed for normal development. As a result, one of the X chromosomes becomes inactive and coagulates into a compact clump of chromatin, called the “Barr Chromatin Body” or “Barr Body” in honor of its discoverer.

The Barr Chromatin Body was discovered in 1949 by Constance Barr and Ernest Hempstead. Although the Barr body contains no active genes, it is not useless. On the contrary, it plays an important role in regulating gene expression, not only on the X chromosome, but also on other chromosomes.

Barr bodies can be detected in female cells by staining chromosomes under special conditions. The presence of a Barr body is one of the ways to determine the sex of the fetus during pregnancy, and can also be used in medical research to diagnose certain diseases associated with abnormalities in the number or structure of chromosomes.

In conclusion, the Barr Chromatin Body is an important part of the genetic information of the female body. Although it does not contain active genes, it plays an important role in regulating gene expression and can be used in medical research to diagnose a number of diseases.

The Barra body is a stable ultraviolet chromosome extension that is found in the nucleus of the body's cells. Barra bode in different tissues have different shapes and chromatin contents. Barr-Chromatinone bodies in normal nuclei occur after 50 years. In the nuclei of cells maturing during dysplasia, Barra bodies of chromatic filaments are also found. Their presence is of clinical significance in the differentiation of papillomas in laryngeal papillomatosis (gynophoroid gland and rectal tissue). In mammals and humans, the multiple presence of Barr's bodies in germ cells is characteristic of women. It is also possible that they are present in the endometrium, the yellow substance of the vascular glomeruli. With long-term syphilis in females, close contact between Barr's bodies and pale bodies leads to the appearance of the "Hassis body". Their number allows us to determine the stages of acquired syphilis. "Barr's body" is different in that it does not contain desmin, a fibrillar protein that regulates nuclear activity over time. While in the cytoplasm, the threads of dehydrated chromatin form polymer network structures - the chromatin nucleolus.