Xanthinuria

Xanthinuria (xanthinuria) is a hereditary disease in which there is an increased level of xanthine and caffeine in the urine. The disease is associated with the enzyme uricase, which is responsible for the metabolism of purine bases contained in DNA, RNA and some vitamins. With pathology, the body cannot effectively utilize purines from the diet, and they remain in the urine and blood. As a result, hyperxanthinimia occurs - an increased content of xanthines in the blood and urine. This disease is rare and manifests itself in the form of sharp abdominal pain, increased urination, agitation, and vomiting. Typical for children of preschool and early school age. Treatment requires a diet limiting purines and prescribing medications to help the body utilize these substances.