Diabetes Phosphate

Phosphate diabetes (diabetesphosphaticus), also known as phosphate nephropathy, is a rare, incurable kidney disease characterized by damage to the kidney tubules due to elevated levels of phosphate in the blood. As a result, inflammation and suppuration may occur in the kidneys, which can lead to renal failure and death of the patient.

The most common causes of diabetic phosphate nephropathy are type 2 diabetes, which affects 30-50% of patients, and diuretics, drugs that remove excess fluid from the body through the kidneys. Although diabetes and diuretic drugs are the main causes, there are and other factors that increase the risk of diabetic phosphate disorder are various kidney diseases in people with diabetes, poor diet, vitamin D deficiency, age and genetic predisposition.

Clinical symptoms of diabetic phosphate disease may include swelling, painful urge to urinate, decreased urine output, low sugar levels, and high levels of phosphate in the urine. If you suspect diabetic phosphate nephropathy, it is very important to immediately consult a nephrologist or endocrinologist for diagnosis and treatment. Diagnosis of phosphate diabetes includes urine and blood tests, CT scan or ultrasound of the kidneys. Treatment may include dietary changes, use of proton pump inhibitors, and treatment of the cause of diabetic nephropathy. If the complication is severe, a kidney transplant may be required. In general, phosphate phosphates pose a serious threat to the patient's life, and timely consultation with a doctor

Diab. phosphate. - iris vulgaris - a sugar disease caused by impaired glucose tolerance: a decrease in the number of insulin-dependent peripheral receptors, an increase in the concentration of triglycerides in plasma and acidosis. It is characterized by the fact that, despite normal or elevated blood glucose levels, glucose from the islet punctate does not penetrate into the blood. Early signs of D.P. characterize the picture of hyperglycemia. The subclinical phase of the disease is characterized by a loss of glycemic profile; hypoglycemic symptoms may appear under the influence of nutritional hemodynamic stimulants. Clinically, diabetes clearly develops in severe forms, smaller islet sizes, and in advanced acyclic processes. The first symptom of the clinical picture of D. p. is vilentia: suddenly there is a feeling of severe weakness, malaise, and a rapid heartbeat appears. On examination: the skin is moist with a yellow tint to the skin of the hands and feet. At the temples, hair falls out in the form of thin threads. The face is puffy, edematous. Often the fingers acquire a pasty shape, the hands become pigmented, their color depends on the duration of the disease. Sometimes these changes are accompanied by the appearance of metric deformations. Hypotony of the skin and hair loss over large surfaces of the body are a consequence of myocardial damage. The patient's condition gradually worsens: weakness, convulsions, coma, and epileptiform seizures appear. The most typical localization of the pathological process is the pancreas, in the periglandular tissue; the chronically inflammatory process takes sizes up to 20 cm or more. Splenomegaly is observed in most patients. The rupture of the acute process occurs against the background of exacerbation of chronic infection. Very rarely, the disease develops acutely, proceeds violently, and is accompanied by vomiting and diarrhea. Mortality 30 - 40%. The diagnosis of D.F. is established on the basis of data on impaired tolerance to carbohydrates: impaired fasting glycemia, latent glycosuria, glycosuria after exercise. Complications are clinically detected in the decompensation phase. The child's condition is serious: toxic-allergic brain damage, infections, multiple organ dysfunction. Determination of the electrolyte composition of serum makes it possible to clarify some features of the clinical picture of the disease. A significant decrease in blood and urine phosphate is associated with an increased content of calcitriol and hyperparathyroidism, as well as with disturbances in phosphorus-calcium metabolism. Hyperphosphaturia is combined with increased excretion