Fibromatosis Congenital Familial

Fibromatosis Congenital Family: causes, symptoms and treatment

Familial congenital fibromatosis, also known as familial congenital fibromatosis or FCF, is a rare genetic disease that is characterized by the formation of connective tissue tumors called fibromas. These fibroids can occur in any part of the body, but they are most common in the arms and legs.

The causes of congenital familial fibromatosis are associated with heredity. Most cases of congenital familial fibromatosis are caused by a mutation in the gene responsible for the growth of connective tissue. If this gene is found in several copies in the body, it can lead to the development of congenital familial fibromatosis.

Symptoms of congenital familial fibromatosis may vary depending on the location of the fibroids. These are usually soft, painless tumors that may increase in size over time. Tumors can put pressure on surrounding tissue, causing discomfort or loss of function.

Treatment for congenital familial fibromatosis may include surgical removal of fibroids if they cause discomfort or threaten health. However, since congenital familial fibromatosis can lead to the appearance of new tumors, surgical treatment may not be effective in the long term. This may require more radical treatments such as radiation therapy or chemotherapy.

In conclusion, congenital familial fibromatosis is a rare genetic disorder that can lead to the formation of connective tissue tumors. Treatment of this disease can be complex and requires an individual approach, depending on the location of the tumors and their size. If you suspect congenital familial fibromatosis, consult your doctor for diagnosis and treatment.

Fibromatous dysplasia (polyfibromatosis) is a clinical, genetic and phenotypic heterogeneous disease characterized by excessive proliferation of mesenchymal cells with the formation of post-inflammatory hypercellular fibromatous nodes and their spread throughout the body, both in soft tissues and throughout organs and systems. There is a significant increase in morbidity and mortality of patients, often leading to disability. The disease manifests itself from birth or in the early stages of intrauterine development, first manifesting itself mainly as skin deformations, but with a high probability of naturally manifesting lesions of other organs and systems. The introduction of molecular biological methods has made it possible to identify several variants of genetic defects. Most cases of the disease are associated with damage to the gene located on chromosome 5q14.3 and encoding one of the regulatory subunits of histone deacetylases, SHFM1. In many cases, FFD is a consequence of defective inheritance, with people with certain genotypes more likely to develop the disease.\n\nThe 4SH3 family is a family of proteins involved in various cellular processes in cells of all three