Ponce Polyarthritis

Ponce Polyarthritis: Symptoms, Diagnosis and Treatment

Ponce polyarthritis, also known as tubercular arthritis or tuberculous polyarthritis, is a rare but serious disease that is characterized by inflammation of the joints as a result of an active tuberculosis infection in the body. This condition refers to extra-pulmonary manifestations of tuberculosis, when the infection spreads beyond the lungs.

Ponce polyarthritis usually develops in individuals suffering from active tuberculosis, but in some cases it may be the first clinical manifestation of the disease. It is characterized by inflammation of several joints, most often large ones such as the knees, elbows, shoulders and ankles. Patients may experience tenderness, swelling, and limited movement in the affected joints. In some cases, high fever and general weakness may occur.

Diagnosis of Ponce polyarthritis includes the patient's medical history, physical examination, laboratory tests, and instrumental examinations. An important element of diagnosis is the identification of active tuberculosis infection in the body. This may require collection of sputum for analysis, chest x-ray, computed tomography and other examination methods.

Treatment of ponce polyarthritis is based on complex therapy, which includes anti-tuberculosis drugs and treatment of joint inflammation. Anti-TB drugs such as isoniazid, rifampicin, pyrazinamide and ethambutol are prescribed to kill the TB infection. In parallel, anti-inflammatory drugs such as nexstatin, nimesulide and glucocorticosteroids are used to relieve symptoms of inflammation and joint pain.

In some cases, surgery may be required to drain the joint or remove necrotic tissue. Physiotherapy and rehabilitation exercises also play an important role in restoring joint function and preventing deformity.

The prognosis depends on the degree of activity of tuberculosis infection and the timeliness of starting treatment. With timely and adequate treatment, most patients achieve full recovery and restore the function of the affected joints. However, if the infection is advanced and treatment is delayed, complications such as joint deformities and dysfunction may occur.

Prevention of ponce polyarthritis is associated with effective control and treatment of tuberculosis. Vaccination against tuberculosis (BCG) can help reduce the risk of developing active infection, including extrapulmonary manifestations. It is also important to maintain hygiene measures, avoid contact with people with tuberculosis, and follow infection prevention guidelines.

In conclusion, ponce polyarthritis is a rare but serious disease associated with tuberculosis infection. It is characterized by inflammation of the joints, which requires complex treatment, including anti-tuberculosis drugs and anti-inflammatory drugs. Early detection, diagnosis and treatment play an important role in preventing complications and achieving full recovery for patients.

Ponce polyartitis is an inflammatory joint disease associated with infection caused by _Mycobacterium tubercuosis_. Joint damage in ponce arthritis is caused by a delayed-type hypersensitivity reaction to this infection. Attempts to connect the development of ponce polyartitis with any variant of the immune response are not supported in practice. In developed countries, primary cases have become less common, and in many Asian countries they persist even today in the form of epidemic outbreaks or sporadic cases. When clarifying the diagnosis, patients with ponce polyarthritis should be correctly classified not as tuberculosis, but as non-tuberculosis forms of infection.

In the affected skin tissue, microbial cell antigens are deposited from the immune complex, which play a role in the development of sensitization to _Mycobacterium_ spp. It is accompanied by weak, spontaneous activity of lysozyme and properdin, increased levels of gammaglutamyl transpeptidase, and immunity to new antigens of tuberculosis nature. The complaints presented by patients are nonspecific. Characterized by lethargy, weakness, weight loss, periodic fever up to 38-39°. The joints of the hands and feet gradually atrophy, asymmetrically and monopolarly, in the initial period proximally