Wilms tumor

Wilms' Tumor: Understanding and Perspectives

Wilms tumor, also known as Wilms tumor, is a rare genetic disorder that affects the development of connective tissue in the body. This disease was named after Dr. August Wilms, who first described it in 1892. Wilms tumor occurs in approximately 1 case in 20,000-50,000 newborns.

Characteristics of Wilms tumor include physical and psychological symptoms, which may vary depending on the severity of the disease. Physical signs include joint hypermobility, unusual facial features (such as long ears, wide mouth, long pointed nose), and delayed skeletal development. Psychological symptoms include mental retardation, problems with learning and social adaptation.

Wilms tumor is caused by a genetic defect that results in the removal of a small piece of DNA on one of the chromosomes. This defect affects the production of the protein elastin, which plays an important role in the development of connective tissue. Lack of elastin leads to the characteristic physical and psychological manifestations of Wilms tumor.

Although Wilms tumor is considered an incurable disease, there are treatments and support available to help patients manage symptoms and improve their quality of life. Medical support includes physical therapy to strengthen muscles and joints, specialized training to develop social skills, and behavioral therapy to improve behavioral health.