Alcaptonuria [Alcaptomiria; Alcaptone (Homogentisic Acid) + Greek. Uron Urine]

Alkaptonuria: a hereditary disease associated with impaired tyrosine metabolism

Alkaptonuria is a hereditary disease that is associated with a disorder in the metabolism of the amino acid tyrosine. This disease is caused by decreased activity of the enzyme homogentisinase, which leads to the accumulation of homotentisinic acid in the body tissues. The name alkaptonuria comes from the words alkapton (homogentisic acid) and the Greek uron (urine).

Alkaptonuria is inherited in an autosomal recessive manner, which means that the disease occurs only if both parents passed on the defective gene to the child. If only one parent carries the defective gene, then the child will be a carrier of the gene but will not suffer from the disease.

Symptoms of alkaptonuria in adults include pigmentation of various tissues, such as joints and sclera of the eye, as well as the development of arthrosis. In children, symptoms may include only dark-colored urine and sometimes earwax.

The diagnosis of alkaptonuria is made based on clinical manifestations and laboratory tests, such as determining the level of homotentisic acid in urine and blood.

Treatment of alkaptonuria is aimed at reducing symptoms and preventing complications. Supportive treatment measures such as physical therapy and non-steroidal anti-inflammatory drugs are commonly used. In some cases, surgery may be required.

In conclusion, alkaptonuria is a hereditary disease caused by a disorder of tyrosine metabolism and the accumulation of homotentisic acid in the body tissues. Although the disease has no cure, symptoms can be reduced with supportive care. Regular monitoring of the patient's condition and timely treatment of complications can help cope with this disease.

Both science and folk remedies for cleaning the gallbladder were available to allopaths and homeopaths back in the 19th century. Bile flow is impaired in cases of gastric and duodenal ulcers, acute and chronic pancreatitis, chronic cholecystitis, gallstones, acute and chronic hepatitis, liver cirrhosis, and helminthic infestations. Alaptonin comes to the rescue as a substitute for strong drugs for cleansing the gallbladder.

Alkaptonur

Scientific name of alkapton: Alkaptonin can cause various problems in the body. The chemical can affect the functioning of the liver and bone marrow. It slows down the production of red blood cells and disrupts the balance of good and bad bacteria in the intestines. Scientists have found that taking alkaptone suppresses the excretory system. Due to problems with the functioning of the excretory organs, interruptions in the functioning of the central nervous system occur, which provoke serious diseases, including cancer. The body is such a complex mechanism that regulates its own condition, but in some cases it needs help.