Gliomatous Pins

Gliomatous pins are growths of neuroglia in the form of cords along the gray matter of the spinal cord. Such growths are observed in syringomyelia, a disease in which cavities filled with cerebrospinal fluid form in the spinal cord.

With syringomyelia, the nerve fibers and neurons of the spinal cord are destroyed. In response to this, gliosis develops - the proliferation of neuroglia. A feature of gliosis in syringomyelia is its localization - it spreads along the gray matter of the spinal cord, forming cords. These growths of neuroglia are called gliomatous pins.

Gliomatous pins are characteristic of syringomyelia. Their presence helps to diagnose this disease and distinguish it from other spinal cord pathologies. In histological examination of spinal cord biopsies, gliomatous pins have a characteristic morphology that makes it possible to recognize syringomyelia.



Glioma or gliomatosis of the spinal cord is a disease that is characterized by the proliferation of neuroglial cells along the white and gray matter of the spinal canal. Most often this occurs as a result of hereditary disorders in the genetic material. This diagnosis is usually made after birth. However, regardless of the cause of occurrence and conditions of development, gliomas in the spinal cord have a negative impact on the quality of life and can lead to disability or even death of a person. Gliomas can form in various pathologies of the nervous system, including hereditary anomalies, infections, intoxication and trauma. In addition, spinal cord glioma



Syringomylia (syrinx) is a neural abnormality in which jelly-like strands of neuroglia are deposited and move within the nervous tissue. Neurological disease from the group of myelodysplasias. The prevalence of syringomyelia is unknown, but patients make up no more than 0.5% of the population, the incidence is 0.2%. Syringomylia is characterized by an early onset of pain. By the time the diagnosis is made, half of the patients have symptoms of pain sensitivity and muscle deformities. According to various authors, the frequency of involvement of individual muscle groups ranges from 82.9–99.8%. More often than others, the muscles of the proximal torso, lower back, buttocks and legs are affected, primarily the thigh, lower leg, and calf muscles. The disease often occurs in women aged 30 to 60 years. 50% of men and 73% of women have combined eye pathology, 20% suffer from ataxia. Hotha-Spitzner sclerosis can mimic the clinical picture of meningioma, but syringomyelia is characterized by a total spread of neuroglial tissue with invasion of gray matter. One of the research methods is transcutaneous electromyography. However, today it is used clinically as a simple adjunct to broader research. The intradermal injection contains hyaluronic acid, which causes irritation and swelling of the skin. The electromyogram is more sensitive in the early stages, when changes are smaller. An important aspect of the differential diagnosis of syringomylia is MRI. Unlike other peripheral motor neuron diseases, MRI usually contrasts syringomas, indicating a spinous location along the spinal cord. MRI typically highlights a wide range of heterogeneous heterogeneities, most often present in the form of interstitial infiltrates. MRI clearly shows the inflammatory localization of the process, the destruction of the white medulla in the form of an oval-teardrop-shaped spinous gradient and the ability of the typical granular grayish-white infiltration to hydrolyze the ricket.