Koline-Kaplan Syndrome

Colin-Kaplan syndrome

Colin-Kaplan syndrome is a rare disease characterized by delayed puberty and disturbances in the functioning of various body systems in men. It was first described by the American pediatrician D. Koline and his colleague D. Kaplan at the beginning of the 20th century.

Koline-Kaplan syndrome is characterized by the fact that adolescents and young adults look much younger than their peers and do not have sufficient muscle mass, and also do not go through puberty. At the same time, men may be prone to obesity.

Symptoms of Koline-Kaplan syndrome may include work disturbances

Colin Kaplan syndrome is a complex of disorders manifested by an increase in the size of certain organs, such as the heart or liver, and accompanied by dysfunction of these organs. One of the first mentions of this syndrome is found in the book “Quenching of Ailments” (editions of 1638 and 1705

Kolina Kaplan syndrome

Kolina Kaplan syndrome (previously used as a synonym - “Dowdy-Weber syndrome”) is a rare congenital disease that leads to disruption of the nervous system and the appearance of many symptoms, including visual and hearing abnormalities, paresis and impaired coordination of movements. The disease most often occurs in girls, usually under the age of 6 years.

The child exhibits a number of neurological symptoms that begin in utero. Often, a child may be born with hydrocephalus, which complicates treatment and prognosis, but nevertheless helps to find the causes of the syndrome. Already in utero children suffer from swallowing and breathing at a level significantly different from the norm, and after birth they have significant limitations in head movement, so many have neck deformation. Babies born may also have facial defects: the large tongue is curved and inverted, the lower jaw is too heavy and enlarged, and the upper eyelids are covered below, which interferes with normal movements. Because of all these symptoms, the child cannot eat properly - he has to force food into his mouth almost by force or raise his head above chin level. They may also have hearing problems due to their large ears. Most of these defects are caused by abnormalities in the development of the pharyngeal pouch, which contains the nerves that provide the motor function of the diaphragm. The child's brain is also significantly changed: its shape is slightly elongated towards the front, and