Polyserositis Recurrent Familial

Recurrent familial polyserositis (polyserositis recidiva familiaris) is a rare autoimmune disease characterized by recurrent inflammation of the serous membranes (pleura, pericardium, peritoneum, vaginal testicular membranes), occurring with the accumulation of exudate in the serous cavities.

The disease usually manifests at a young age. It is inherited in an autosomal dominant manner with incomplete penetrance. The pathogenesis is based on a violation of immunoregulation with autoimmune aggression against antigens of the serous membranes.

Clinically manifested by repeated attacks of fever, pain in the chest or abdomen, shortness of breath, cough, sometimes ascites, hydrothorax, hydropericardium. The diagnosis is confirmed by the detection of exudate in the serous cavities, increased ESR, and hypergammaglobulinemia.

Treatment includes taking glucocorticoids, cytostatics, and antimalarial drugs. The prognosis is generally favorable, but severe relapses are possible.

Every person sooner or later faces various diseases, and most of them require long-term treatment. One of these diseases is polyserositis. Although it may not seem serious to healthy people, to a patient with a weak immune system it is a real problem that needs to be addressed urgently.

What is polyserosite? Polyserositis is a disease that affects the serous membranes that cover the lungs, heart, liver and other organs in the human body. Serous membranes produce a clear fluid called aqueous that protects organs from infection and injury. However, with polyserositis, this fluid is retained or even forms compacted formations. This process can be caused by various factors