Posterior Fossa Syndrome

Posterior fossa syndrome is a rare genetic syndrome clinically manifested by deafness, mental retardation, recessive epilepsy, optic atrophy and other ocular pathophenotypic features of Dandy–Walker syndrome. The disease is hereditary and is inherited according to an autosomal recessive mechanism. Dandy-Walker syndrome is one of the possible causes of treatment-resistant refractory intestinal obstruction and requires immediate exclusion in appropriate cases. The disease can also cause a delay in the maturation of motor neurons. An important characteristic of the syndrome associated with the age aspect is the high risk of developing neurocognitive deficits in children. One of the most effective and safe ways to prevent this syndrome is preimplantation diagnosis performed before embryo transfer (PD method).

An inherited pattern of behavior in which genetic preconditions are used to promote or facilitate the achievement of positive outcomes is usually called positive genius. However, a meta-analysis has shown that such behavior may also be pathogenic, especially within inherited syndromic behavior, and has been proposed as an alternative term "hereditary epilepsy with negative feedback features" to distinguish between positive and negative

Posterior fossa syndrome is a neurological disorder that occurs due to abnormal anatomy or physiological changes in this area of ​​the brain. A person suffering from posterior fossa syndrome may experience a variety of symptoms, including headaches, vision loss, dizziness and fainting.

The origin of posterior fossa syndrome is still unknown, although it is generally believed to be caused by an imbalance between the nerve signals traveling from the brain to the eyes. This could cause various problems in the optic nerves, including vision defects, changes in brightness and sensitivity, and difficulty focusing. It is known that posterior fossa syndrome can be congenital or acquired. In the case of a congenital nature, such a pathology is observed already at the earliest stages of the development of the ocular nerve bundles. But in the case of acquired pathology, the reasons can be very diverse and uncertain. They may relate to the occurrence of tumors, vascular thrombosis, head injuries, infectious diseases, inflammatory processes of the eye membranes, etc. It is important to remember that self-diagnosis and treatment of this disease is unacceptable without consultation with a specialist. Any onset of unpleasant symptoms should be promptly examined by an ophthalmologist.