Marble-Bone Disease

Marble disease, also known as Osteopetrosis, is a rare inherited disease that is characterized by unusual bone density. This causes bones to become brittle and prone to fractures. Marble disease can manifest itself in different forms, from severe cases leading to death in early childhood, to milder forms that can only be detected by random examination.

One of the main causes of Marmora disease is a genetic mutation that affects the formation and functioning of the cells responsible for the destruction and regeneration of bones. As a result, the bones become denser and less capable of rebuilding and replacing damaged areas. This causes bones to become brittle and prone to fractures, as well as other health problems such as anemia, dental and hearing problems.

Symptoms of Marmora disease may include bone pain, susceptibility to fractures, fatigue and weakness, and problems with teeth and hearing. Diagnosis can be made based on a physical examination and tests for genetic mutations.

Marble disease has no cure, but symptoms can be managed with various treatments such as bone therapy, bone marrow transplant and hormone therapy. Physical therapy and other rehabilitation techniques may also be helpful.

In conclusion, Marble disease is a rare but serious condition that can lead to various health problems. Early detection and treatment can help improve patients' quality of life and prevent possible complications. If you suspect you have Marmora disease, consult your doctor for advice and diagnosis.

Marble disease, or osteopetrosis, is a chronic, genetically determined and progressive skeletal disease with impaired bone formation. Reduction of bone mass by up to 35% due to excessive growth of its intraosseous skeleton (sclerosis). 1 in 30 thousand children are affected. The global prevalence averages 280 cases per million population. In the structure of hereditary pathology in children, osteopetrosis and congenital deafness take second place.