Grenblad-Strandberga Syndrome

Grönblad-Strandberg Syndrome: Description and Clinical Aspects

Grönblad-Strandberg syndrome, named after the Swedish ophthalmologist E.E. Grönblad and Norwegian dermatologist J.V. Strandberg, is a rare genetic disorder with many clinical manifestations. This syndrome is described for the first time in the scientific literature and is a combination of ophthalmological and dermatological abnormalities.

Patients suffering from Grønblad-Strandberg syndrome usually show symptoms in early childhood. One of the characteristic symptoms is skin pigmentation, which manifests itself in the form of spots or pigmentary changes on various parts of the body. These changes can vary in shape, size and location. In addition, some patients may also have skin abnormalities such as atrophy or hypertrophy.

An important clinical feature of Grönblad-Strandberg syndrome is eye abnormalities, which may include cataracts, glaucoma and other vision defects. Patients may also experience vision problems such as farsightedness or nearsightedness. Ophthalmic complications can significantly affect the patient's quality of life and require specialized treatment and care.

Genet

Grenblad-Strandberg syndrome - Grenblad-Strandberg syndrome (syn.: group A) - The term was introduced by the Swedish ophthalmologist E. Groenblada and the American dermatologist J. V. Strandberg in 1960.

**To make a diagnosis, a combination of the following signs is necessary:** • bilateral inflammatory erythematous swelling of the eyelids; • triad of symptoms: lacrimation + photophobia + conjunctival hyperemia; • formation of ulcerations and scars on the mucous membrane of the upper and lower eyelids or in the area of ​​transition from the inner and medial canthus.