Pancreatitis phlegmonous is an acute purulent inflammation of the pancreas, limited to the limits of its capsule. It is characterized by inflammation and destructive changes in the glandular tissue of the organ. With pancreatic necrosis, parenchymal and interstitial structures are involved in the process - parenchyma, large ducts, blood and lymphatic vessels. Along with this, there is lymphoplasmacytic infiltration in the regional lymph nodes and in the portal system, sometimes paranecrotic infiltration occurs beyond its boundaries. In 20% of cases, necrosis spreads to neighboring organs - the stomach, bile ducts, diaphragm, peritoneum. Pancreatitis and phlegnotic type make up about 2/3 of all acute surgical diseases of the hepatopancreatoduodenal zone and abdominal organs, and are their most severe form. The mortality rate for this form of pancreatitis ranges from 44% to 50%. In the process of acute pancreatitis, from one to three percent of the cells of the exocrine zone of the gland die. However, this process leads to progressive multifocal organ dysfunction; almost all organs and systems, including the cardiovascular system, can be involved in the pathological process through reactive pancreatic shock - the patient’s death can occur from multiple organ failure. Treatment of “prehistoric” forms of pancreatitis involves the impossibility of immediate removal of the gland and is inappropriate due to the increased risk of postoperative mortality and postintestinal complications. Elimination of the source of destruction of the glandular substrate is accompanied by a sharp decrease in the number of patients with septic nature of destruction