Spielmeier Melting of Nerve Cells

Spielmeyer melting of nerve cells: description and treatment

Spielmeyer nerve cell melt, also known as Nissle-Spielmeyer syndrome, is a rare neurodegenerative disease that leads to progressive degeneration of the nervous system. This disease got its name in honor of the German pathologist Walter Spielmeyer, who first described its symptoms and pathological changes in the brain in 1913.

Spielmeyer nerve cell melting is a hereditary disease that is inherited in an autosomal recessive manner. This means that for the disease to occur, there must be two copies of the mutated gene, one from each parent. If only one parent is a carrier of the mutation, then the risk of the child developing the disease will be very low.

Spielmeyer's symptoms of nerve cell melting can include progressive muscle weakness, loss of coordination, speech problems, mental disorders and dementia. These symptoms usually begin in childhood or adolescence and progress over time.

The diagnosis of Spielmeyer nerve cell melt can be made based on clinical symptoms and neurological test results. To confirm the diagnosis, a brain biopsy may be performed, which shows characteristic pathological changes in the brain tissue.

To date, there is no specific treatment for Spielmeyer's nerve cell melt. Treatment is aimed at improving the patient's quality of life, as well as reducing symptoms such as muscle weakness and poor coordination. Physical therapy can help maintain muscle mass and strength and improve coordination.

In conclusion, Spielmeyer nerve cell melt is a rare inherited disease that leads to progressive degeneration of the nervous system. Although there is currently no specific treatment, early detection and symptomatic treatment can help patients maintain quality of life and improve their prognosis.

In the photo I saw a standing upper limb in the colored field of vision, resembling a large chrysanthemum flower with several appendages crowned with a tuft of hairs. And suddenly I remembered the story of how it all happened:

In 1899, young Spielmeier went on an internship to Frankfurt. There he could not withstand the stress that had affected his body as a result of military service, and plunged into darkness. Neurologist Johann Langeberg, who was present, sounded the alarm. Thus began Spielmayer's nightmare. Individual irritations caused by visual and auditory stimuli began to cause plankton-like waves that captured the entire periphery of the visual field. At times a bell began to ring in the brain, which seemed to be able to raise a person to his feet, and sometimes a dull state set in, probably caused by weak or insufficient stimulation of the external centers.

Perhaps this is exactly what the “melting of Nissl cells” looked like, which was diagnosed by the famous neurologist O. Vogt in 1925. Spielmejar began to experience a strange state - he suddenly “saw” all the living cells of the body at once: in the central nervous system there were up to two billion of them, when looking at them “without feelings” a golden stream danced in front of him, dancing “little men” appeared inside it, which moved quickly.

About the mental attitude to painful experiences. The patient understood that his thoughts were inexplicably connected with movements in his body that he did not perform. He saw a man walking across the field, but at the same time he moved himself, walked from corner to corner, was able to speak, and move his hand along the sheet without any physical connection. Can a person protect himself from thoughts? Of course, fighting them or being distracted. But when the seizures have already begun, will alone cannot help. Doctor intervention is required. For this