Apoplectiform syndrome

Apoplectiform syndrome (syndromum apoplectiforme; from the Greek "apoplektikos" - struck by a blow and the Latin "-formis" - similar) is a syndrome of acute focal brain damage, manifested by sudden loss of consciousness, disturbances of movement and sensitivity.

Clinically, the syndrome resembles a stroke, but unlike it, the cause of apoplectiform syndrome can be fainting, seizure, brain tumor, brain abscess, encephalitis and other pathological processes.

The main symptoms of apoplectiform syndrome are:

1. Sudden loss of consciousness

2. Hemiparesis or hemiplegia (unilateral paresis/paralysis of the limbs)

3. Speech disorders (aphasia)

4. Visual impairment

5. Headache

6. Nausea and vomiting

Diagnosis of apoplectiform syndrome includes a neurological examination, CT or MRI of the brain, cerebrospinal fluid analysis and other studies to clarify the cause of the disease. Treatment is aimed at eliminating the underlying pathological process in the brain. The prognosis depends on the etiology of the syndrome and the timeliness of therapy.

Apoplexiform syndrome is a rare hereditary disease that causes disturbances in the functioning of the nervous system and leads to various forms of anomaly. In this article we will take a closer look at the history and symptoms of apoplexiform syndrome, as well as treatment methods.

The occurrence of apoplexy syndrome was discovered in 2004 by Swiss geneticists while conducting a study of mutations in the GAPDH gene. This gene codes for the enzyme glyceraldehyde-3-phosphate dehydrogenase, which is involved in energy production in cells. Patients with GAPDH mutation syndrome exhibit impaired functioning of the nervous tissue, which impairs the functioning of