Horton-Magath-Brown Syndrome

Title: Horton-Magath-Brown Syndrome

Horton-Magath-Brown Syndrome - (v. t. horton, born in 1895, American doctor; t. v. Magath, modern American doctor; g, e. brown, 1885-1935, American doctor ).

Horton-Magath-Brown Syndrome was first described by American doctors W.T. Horton (b. 1895), T.W. Magathom (modern American physician) and J.E. Brown (1885-1935).

This syndrome is characterized by chronic inflammatory vascular disease, mainly of the temporal artery, which leads to its necrosis and ulcer formation. The main symptoms are severe headaches in the temporal region, fever, and general malaise.

Diagnosis of Horton-Magath-Brown Syndrome is based on medical history, clinical picture and results of laboratory and instrumental studies. Treatment includes the administration of glucocorticosteroids and cytostatics to suppress inflammation in the vessel wall. The prognosis with timely diagnosis and treatment is favorable.

Thus, Horton-Magath-Brown Syndrome is a rare cerebrovascular disease described by three American doctors in the first half of the 20th century. Correct and timely diagnosis of this syndrome is extremely important to prevent the development of irreversible changes and preserve the patient’s health.



Horton-Mahat-Brown syndrome (Horton syndrome) is a hereditary connective tissue disease characterized by a triad of symptoms - preauricular fibrosis, otosclerosis and strabismus.

Diagnosis: a classic three-step diagnosis of Horton's syndrome is carried out. It is based on an earlier version with three diagnostic stages.

The first examination is a consultation with the patient in the clinic. At this point, the hearing specialist asks the patient about symptoms. The second examination (level 2 examination) is carried out six months after the hearing consultation. The diagnosis is made based on two types of criteria: objective and subjective. Objective criteria include physical examination data (objective data), additional examination data (diagnostic tests), and functional indicator data (search for functional disorders). The third examination (i.e. Level 3 examination) is carried out 6 months after the examination at the second stage. The main function of the diagnostic test is to definitively confirm the diagnosis of Horton's syndrome by selecting from three alternative diagnostic solutions; option a – reliable confirmation of the diagnosis; option b – refutation of the diagnosis.

In clinical practice, you can use the classification of symptoms of Horton's syndrome proposed by a Japanese group of doctors (1983). At the same time, for each side of the body (left and right), 4 groups of symptoms are distinguished: the first is preauricular fibrosis, localized directly at the external auditory canal; the second is the lack of function of the ear muscle; third - otosclerosis; the fourth group is strabismus.