Ollier-Casta Dyschondroplasia

Ollier-Caste dyschondroplasia: understanding and characteristics

Ollier-Caste dyschondroplasia, also known as Ollier-Caste syndrome or multiple enchondromatous dysplasia, is a rare genetic disorder that affects bone development and growth. This inherited disorder is characterized by the formation of several cartilage tumors, called enchondromas, within the bone tissue.

The name dyschondroplasia comes from the two leading doctors and researchers who first described this condition. Jules Ollier, a French surgeon (1830-1900), and Antoine Cast, a German physician (1856-1903), made significant contributions to the study of this rare disease.

Ollier's symptoms

Olea Casta (1826/1827 - 08/19/1910) was a French surgeon of Italian origin, a student of Suviin, who described in 1885 a condition later called Casta's osteodystrophy. In Russian-language sources it is often referred to as “ostosis”, ostofibroeositis, or ostophiositis. He also has several other options for the name of his disease: myelitis-syringomyelia (as he himself defined in the diagnosis), craniospinal