Van der Hoeve syndrome (VDS, Van der Hoeve Ocular Motility Syndrome; abbreviated VDSM or VDOMS) is a rare genetically determined disease characterized by dysfunction of both eye muscles and hypertelorism of the middle and lower part of the face, which is found more often in men, than women. This is the main diagnostic condition of visual dystonia (ophthalmic arch).
Van der Hoeve syndrome is a rare inherited disorder that appears early in life and causes changes in eye development. This syndrome was first described by the Dutch ophthalmologist Antonius van der Hoovey in 1933.
Van der Hoeve syndrome is an autosomal dominant disorder, which means that there is a genetic mutation that is passed from parents to children. However, not all people with this mutation will develop van der Hoeven syndrome. Most people who have this genetic mutation and have no symptoms