Agangliosis of the Large Intestine Congenital

Colon aganglionosis is a congenital pathological condition characterized by the absence of elements of the nervous system on the wall of the colon. In the vast majority of cases (80%), a defect in the development of villi is determined, causing an anatomical anomaly in the structure of the mucous membrane of the colon wall, leading to disruption of the passage of feces through the colon.

Congenital agangliosis coli Introduction Today we look at agangliosis coli, a rare genetic disorder in which there are no nerve cells in the intestine. This condition is known as agangliodiapepsia. Congenital angelodiaprepsia affects the body's absorption of nutrients and can lead to serious health complications. Here's a brief explanation of how it occurs and how to treat it in children.

Agangliodes of the colon is a hereditary disease Agangliodes develops when, during the prenatal period of development, the nerve cells (ganglia) that form the nerve network in the intestinal tissues are underdeveloped. The consequence of this deficiency is a disruption of connections between nerve cells and intestinal muscle tissue. From

Colonic aganglionosis is a congenital absence of nerve endings in the mucous membrane and submucosal layer of the intestinal wall.

A hereditary predisposition to the disease, or the presence of a sick child in the family, is indicated in 98% of patients. 75% have indications of the birth of a sister or brother with this pathology. The disease is diagnosed mainly in boys, the ratio to girls is 3:1.

**Congenital aganglionosis** **Colon** is a developmental anomaly of the wall of the colon, in which there are no ganglia of the sympathetic nervous system in its walls, and even some ganglia are also absent in the wall of the adjacent section of the rectum. That is, there is a complete loss of the ganglion