Genodermatosis

Genodermotosis is a group of inherited skin diseases that are associated with changes in genes encoding proteins involved in the development and maintenance of skin health. These diseases can present with a variety of symptoms such as pigmentation, changes in skin texture and thickness, ulcers or scars. Some genodermotoses may be associated with the development of skin cancer and other malignancies. Treatment for genodermatosis can vary depending on the specific disease and may include surgical procedures, medications, or a combination of these methods. In this article we will look at the main types of genodermoses and methods of treating them.

Genodermosis is a serious disorder that is manifested by disorders of skin pigmentation, stretch marks on the skin, and a tendency to scar formation. It is a congenital disease, so it cannot be avoided without the help of a doctor and visits to hospitals. The culprits for the appearance of a congenital type of disease are not one gene, but many. If it is diagnosed in a timely manner, found and identified, then the desired gene can be found and the human body can be cured.

In theory, more than 574 nosological forms are identified in the group of genodermotiotic conditions - various skin diseases that arise as a result of mutations not in one gene, but in several, or in one of many genes encoding a chain of protein components necessary for the normal development and functioning of the skin, provided that these proteins normally carry out their function in the skin. For example, if a protein chain includes a protein necessary to fight bacteria, microbes, rashes or inflammation in the skin, then when a unit that does not perform any function is replaced, a number of gene and protein mutations occur. If such a gene or protein is optional, then a person can live a normal life only by undergoing appropriate preventive treatment. However, this is basically just a theory; in practice, over time, the number increases and scientists are slowly reducing the frequency between types, provoking the creation of the most accurate and new and effectively working diagnostic algorithms and treatment methods. Therefore, from time to time, statistics are supplemented not only with new types of skin disorders, but also with new ways to treat it and maintain health. Fortunately, this case is extremely rare, and until recently was very little known. However, gradually in recent years, due to the increasing frequency of visits to doctors by young people and the still growing generation, statistics on “genetic demorotic diseases” began to actively appear in an increasingly wider volume. Features of the disease are a tendency to the appearance of various spots due to improper pigmentation, which is most often to blame for blood, as well as a tendency to form stretch marks and scars, the cause of which, as a rule, is inflammatory processes. Of the most common types of syndrome: - Xenychymosis, follicular keratosis, STRA6 gene mutation (type I)

- Mutation in the BASP1 gene (type