Pyrocatechinamines

Pyrocatechinolines (abbr. PCina) are a class of chemical compounds, one of the types of catecholamines. The name comes from the Greek words "pieroc" - fire, "catheus" - sulfur and amine - amino acid, this compound determines its ability to release heat during oxidation. These are thermolabile compounds and are therefore less stable. Natural PCines are tyramine - glucoside and matein - glycoside of catechol, arising at the stage of transformation of the original tyrosine into catechol. Among the oxidation products of all catecholins, the most thermosensitive is tyramine, which is converted into the PCine substance paracoumarin. Under the influence of enzymes, epicatechullinase and norepinephrine dehyde oxygenase convert PCines into their catechological derivatives - dopamine, adrenaline or adrenaline-like substances - oxymetatelin. During acute oxidation of food products, even more toxic compounds are formed in the body - NO2, NO3 and HCHO, which are highly lipophilic, causing neuromuscular paralysis, hemolysis, protein denaturation, disruption of the cardiovascular system, and the autonomic nervous system. When NO decomposes, nitrogen oxides HNO2 are formed - causes tissue hypoxia and the formation of blood methemoglobin, which increases the risk of developing acute lung injury and depletes the system