Afibrinogenemia Hereditary

__Afibrinemia hereditary__ is a genetic disorder characterized by an abnormal form or absence of fibrin in the blood due to a mutation in the _FIB._ gene

All normal human cells contain approximately the same amount of fibrin, which helps blood clot and wound healing. When fibrin levels are insufficient or absent completely, blood clotting is impaired and the risk of blood clots increases. __Afibrinosis hereditary _ __ is a very rare disease associated with the production of fibrin proteins, which are necessary for the formation of healthy blood clots when blood vessels are damaged. Some patients with hereditary fibrin deficiency may not be able to produce some versions of fibrin prothrombinase, resulting in impaired fibrin production.