Ectomesodermal dysplasia

Ectomesoderm dysplasia

Dysplasia is the most common benign skin disorder among adolescent males in India. Diagnosis is made by visual examination and histopathological examination of skin biopsies. As children increase their growth rate and intensively develop their external structures, the skin is prepared for use as a means of protection. Normal skin or abnormal keratinocyte structure cannot do this. Outwardly, it appears oily and sticky and ages faster. External changes gradually become noticeable to parents, and children themselves can notice them, especially on the hands and face. The appearance of open areas of the body indicates the unsuitability of the stratum corneum for functioning at a superficial level. In 1965, Ebert and Hilfiker described a disease characterized by the presence of many border cells of unclear cellular composition, often seen on the palms and soles of the feet and the scalp, more common in the age group 3-20 years. Observable changes in this type include an increase in the number of follicular bodies on the hair disc, thickening of the nails and changes in pigmentation. With the help of a biopsy, it is possible to distinguish this type from

Ectromembranous tissue dysplasia is a rare and serious condition. It is associated with a violation of the embryological development of the skin, and is one of the manifestations of a group of hereditary genetic syndromes.

There are numerous cases of children being born with various forms of EM tissue dysplasia during pregnancy as a result of impaired development of the embryo or fetus. The classification is represented by several types of dysplasia: * dysplastic hyperemic spots; * Wellcourt-Hagen disease; * Fisher syndrome; * lipodermatosclerosis of newborns.

Hereditary skin and hair dysplasia occurs in association with ectoderm dysplasia. In the formation of hereditary dysplasia in areas of the skin located in places where subcutaneous tissue is deposited (above the knee joint, on the inside of the shoulder and thigh, on the lateral side of the chest and in the pubic area), characteristic symptoms appear. Due to the detachment of epidermal cells, skin folds form abnormally. In infants, there is no smooth transition of the fold to the hair. The skin resembles an orange peel in appearance. The skin is also thin and has a white-yellow-pink color. In young people, the outer layer may have an aplastic appearance, but the inner layer will retain the typical shape of normal skin. A wedge-shaped scar or sh