Lipocalcinogranulomatosis

Lipocalcinogranulomatosis is a rare disease characterized by the deposition of lipids and calcium salts in tissues with the development of granulomatous inflammation.

The disease was first described in 1908 by the Austrian pathologist Jacob Erdheim, which is why it is also called Erdheim-Chester disease.

The causes of lipocalcinogranulomatosis are not completely clear. It is assumed that lipid metabolism disorders and excessive deposition of cholesterol and fats in tissues play a role in its development. This leads to the development of an inflammatory reaction and the deposition of calcium salts, the formation of granulomas and fibrosis.

The disease is more common in middle-aged and elderly men. The main clinical manifestations are enlarged lymph nodes, damage to the kidneys, lungs, liver, and spleen. Recurrent respiratory tract infections are characteristic.

Diagnosis is based on the clinical picture, data from laboratory and instrumental studies. To confirm the diagnosis, a biopsy of the affected tissue is performed.

Treatment includes the prescription of immunosuppressants, glucocorticosteroids, and bisphosphonates. The prognosis depends on the extent and severity of organ damage, and is usually unfavorable.

Lipocalcin granulomatosis Lipocalcinase, also known as lipocalin granuloma, is also called lipodoteranogpulomara, which means that it is a compound of calcium with a lipid - here it occurs with lipids containing two or more rings. The chemical compound is classified as a dioxygenase product or lactone. It is found in various tissues. It can be formed due to a malfunction at the genetic level, or it can also appear in the body as a result of chemical damage.

Lipocalinagrauloma is one of many skin and gastrointestinal diseases known as porphyria syndrome, associated with hypersensitivity to hydrogen peroxide, other halogens and vinegar. When oxygen combines with sulfur under the influence of light or other chemicals, it turns into hydrogen peroxide. There are two main ways to manage these types of porphyrias. This