Neophrenia Kahlbaum

Neophrenia Kahlbaum is a rare neurological syndrome first described in 1976 by Samuil Lvovich Solovyov and Lev Moiseevich Kahlbaum. It is a progressive disease of the central nervous system that is characterized by rapid deterioration of cognitive function, motor impairment, behavioral disturbances, increasing aggression, psychosis, and loss of control over bodily functions. Currently, this disease is known as Kahlbaumer's syndrome or simply Kahlbumeria. The syndrome was named after the author of the first more or less successful work on it - Lev Moiseevich Kalbaum. It was originally published in Russian in the journal Neuropathology and Psychiatry named after. S.S. Korsakov”, and a little later was translated into English. In 2015, neophrenia kalbaum was accepted by the World Health Organization as a disease on the list of non-communicable diseases.

Symptoms of Kahlbaum neophrenia In the early stages of the disease, the following symptoms may be observed: * Apathy and laziness * Decreased activity * Suicidal thoughts or attempts * Perception of oneself as a stranger, unfamiliar to oneself; state of alienation. * Decreasing interest in your life and the people around you. In most cases, a person with neophrenia does not show obvious symptoms. A person can lead a full social life and realize their potential in work and personal life until the condition worsens. Among the first manifestations of dysfunction of cognitive processes, one can highlight a disturbance in memory functioning: deterioration in the reproduction of episodic, semantic memory in the absence of a change in the level of logical thinking. It is important that this dysfunction of the neurocognitive type extends to delayed components of activity (reproduction from sensitized supports). As a rule, the first changes appear with atrophic changes in the white matter of the brain. Cognitive dysfunction is initially expressed by memory impairment - mild amnesia and confabulation (uncritical distortion of facts). Moreover, patients consistently maintain a good level of executive functions. Further progression of the pathological process is characterized by an increase in hypertrophy of the basal ganglia and hippocampus, an increase in the volume of the red nucleus and expansion of the ventricles of the brain, and the appearance of atrophy of the corpus callosum. Long-term severe neurovascular disorders against the background of atrophic changes in brain tissue increase and are clinically manifested by impaired consciousness and damage to the cranial nerves. Which ultimately causes a dysfunctional emotional state. In such patients, a depressed mood is always complicated by a state of tension throughout the body with the emergence of obsessive fears and phobias. Along with emotional symptoms, there appears a loss of control over one’s actions and the actions of others, externally associated with psychopathological arousal and aggression. At the same time, unpredictable behavior in familiar situations is revealed, a loss of the adequacy of one’s own ego with a desire to destroy the world around us. Patients are characterized by a loss of fear of committing prohibited actions and resistance by the mind to common sense. Manifestations of focal lesions of the frontal lobe at the onset of the disease are accompanied by high tone of the whole body and paradox