Rhabdomyosarcoma

Rhabdomyosarcoma is a malignant tumor that develops from striated muscles. Pleomorphic rhabdomyosarcoma can develop in late adulthood; This tumor usually affects the muscles of the limbs. Fetal rhabdomyosarcomas can develop in infants, children, and young adults; these tumors are classified into racemose, which usually develop in the vagina, bladder, ear, etc.; embryonic, most often developing on the head and neck, especially near the orbit; and alveolar, developing at the base of the thumb.

Pleomorphic and alveolar rhabdomyosarcomas are difficult to treat; Racemose rhabdomyosarcomas are treated in a combination: radiation therapy, surgical removal and prescribing special medications to the patient. Fetal rhabdomyosarcoma, if treated early, is usually curable with radiation therapy and specific medications (including vincristine, actinomycin D, and cyclophosphamide).

Rhabdomyosarcoma [1] (lat. sarcomatosis myopathica diffusa, synonym: skeletal muscle myosarcoma, diffuse soft tissue sarcoma, Trousseau's tumor) is a malignant tumor of fibroblasts of skeletal (muscle) cells, less often of connective tissue, originating from muscle tissue. The disease is most common in children under 14 years of age. In 90% of cases, type 4 rhabdomyosarcoma is observed. Its aggressiveness depends on cell differentiation. Liposarcoma and fibroepitheliomas of muscle tissue are also found

Rhabdomyosarcoma should be classified as a rare disease, but it is characterized by a high level of aggressiveness and is a dangerous type of cancer. This type of tumor occurs in children and adolescents. As a rule, this disease appears between the ages of four and fifteen years, but cases of the disease also appearing in adulthood or old age are possible. Often the first symptoms of diseases appear when the patient is fourteen to fifteen years old.

The first type of cancer inherent in this disease is an undifferentiated tumor. In this case, the disease spreads through the soft tissues without the possibility of differentiation. However, the body may already have various types of lesions. In addition, the angiosarcomatous type is considered the most common. Its difference lies in the fact that this malignant type of neoplasm is suppressed by chemicals. However, this type of disease progresses slowly and is difficult to treat. After it, almost ninety percent of patients are doomed to death.