Sneddon-Wilkinson Syndrome

Sneddon-Wilkinson syndrome is a rare disease belonging to the group of vasculopathies. The pathology is manifested by symmetrical lesions of the skin and mucous membranes throughout the body; half of the patients have eye damage. The main symptom is a petechial rash on the skin and bleeding from the mucous membranes, which become brighter after exercise. The disease most often affects people under 40 years of age and can lead to the development of hemolytic anemia. At the moment, no treatment methods have been developed to avoid a decrease in the patient’s quality of life. In cases where drug therapy does not have an effect, organ transplantation is prescribed.

Sneddon-Wilkinson syndrome is a rare skin disorder characterized by multiple lesions and no overall lesions (other conditions, such as psoriasis or eczema, usually have symmetrical lesions).

Sneddon-Wilkins syndrome was first mentioned in 1935 (J. V. Sneddon). This rare skin disease is characterized by multiple, small rashes located on the inner extremities, sides of the face, brow ridges, neck and arms. The main symptoms are those of systemic dysfunction such as chronic fatigue, fever and enlarged lymph nodes, which may persist for a long time before skin symptoms occur. Diagnosis of the disease is based on the appearance of the skin - multiple small cicatricial ulcers throughout the body, and in order to distinguish from other diseases, systemic dysfunction must be excluded, this requires blood tests and immunological studies.