Leucolysin

Researchers in microbiology and medicine are always looking for new ways to combat infectious diseases. One such method is the use of antimicrobial peptides. Leucolysin is one such peptide that is derived from certain types of fish and has strong antimicrobial activity.

Leukolysin belongs to a family of cationic peptides that exhibit bactericidal activity against many types of bacteria. It is found in several species of fish, such as halibut, chum salmon, pink salmon and others, and is a polypeptide chain 25 amino acid residues long.

The action of leukolysin is based on its ability to penetrate the bacterial cell membrane and destroy its structure. The peptide binds to negatively charged phospholipids in the bacterial membrane, which leads to disruption of the integrity of the membrane and the release of cytoplasm from the cell. This leads to the death of the bacterium and prevents its further reproduction.

Leukolysin has a wide spectrum of action against various gram-positive and gram-negative bacteria, including Streptococcus pneumoniae, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and others. In addition, this peptide exhibits activity against fungi and viruses.

Research has shown that leukolysin can be used as an antimicrobial agent in the treatment of infections caused by various pathogens. It can also be used as a food preservative because it has the ability to kill bacteria that cause food spoilage.

In conclusion, leukolysin is an antimicrobial peptide derived from fish that has a broad spectrum of activity against a variety of bacteria, fungi, and viruses. Its use may be of great importance in the fight against infectious diseases and as a food preservative.



Leukocyte lysozyme α-galactosidase is a protein that breaks down bacterial cells by hydrolyzing cell walls and membranes. Contains about 60% glutamine and lysine. Found in many animals and humans. Part of lysocytes (leukocytes). White blood cells contain lysosomes that digest bacterial cells. Lysis of pathogens enters the bloodstream from infectious foci through the vessels of the inner surface of the hollow organs and submucosal layer into the lumen of the hollow internal organs of the abdominal cavity, where they are dissolved by proteolytic enzymes and leukocytes. Leukolysin is also sometimes referred to by the more common name Leukokinase.