Pancreatic necrosis Postoperative

Postoperative pancreatic necrosis is necrosis of the pancreas that develops after surgery on the abdominal organs.

The reasons for the development of postoperative pancreatic necrosis may be the following:

  1. Trauma to the pancreas during surgery. This can occur when the ducts of the gland are damaged or its blood supply is disrupted.

  2. Suffered intraoperative shock. Hypotension leads to decreased blood flow to organs, including the pancreas.

  3. Thromboembolism of pancreatic vessels by blood clots from large vessels.

  4. Reperfusion injury of the pancreas after restoration of blood flow through vessels compressed during surgery.

Clinical manifestations of postoperative pancreatic necrosis: abdominal pain, nausea, vomiting, fever, tachycardia, hypotension. As necrosis progresses, pancreatogenic shock and multiple organ failure develop.

Diagnosis is based on determining an increase in the level of pancreatic enzymes in the blood, visualizing changes in the pancreas with CT, MRI, and ultrasound.

Treatment of postoppancreatic necrosis is complex and includes intensive therapy aimed at combating shock, infection, multiple organ failure, as well as surgical interventions according to indications - drainage of the omental bursa, necrosequestrectomy. The prognosis for postoperative pancreatic necrosis is serious, mortality reaches 20-30%.