Stokes Syndrome

Stokes syndrome.

Stokes (or in other words, paracausal or paradoxical fainting or fainting when exerting, or, as they say in everyday life, “redistribution of blood”) is a sudden loss of consciousness caused by a change in the position of the head. Accompanied by the cessation of the functioning of certain body systems: failure of the cardiovascular system, breathing and parasympathetic nervous system. It often occurs in patients with cirrhosis of the liver with the addition of ascites of the abdominal cavity and torsion of its diverticulum. It can also be detected in the presence of thrombosis of the small intestinal mesentery. Fainting of this type can develop against the background of physical activity and after walking, with age. They usually happen unnoticed by others. The paroxysmal part of the syndrome can last from 2 to 30 minutes. His attacks follow each other with an interval of 1–5 minutes, and then disappear. Weakness of vision, panic fear develops, blood may appear in the sputum, excessive salivation, blocked ears, rapid pulse and shortness of breath, orthostatic collapse and tachycardia, arrhythmia. Gastritis and the erosive process in the small intestine is manifested by vomiting, sudden gas formation in the stomach with pain and belching. Abdominal pain syndrome in the epigastric region is also possible. In this case, diastasis of the white line of the abdomen, diffuse mastodynia, loose hair, brittle nails, convulsive contractions of the muscles of the lower extremities, ulceration of the oral mucosa, bluish rashes under the eyes behave differently. Although a person usually manages to recover on his own or with the help of loved ones, it is always better to go to the hospital.

Stokes syndrome is a rare and dangerous genetic disease that affects the human circulatory and lymphatic systems. In severe cases, the disease can lead to the death of the patient within months or even years of diagnosis. This condition was first described in the scientific literature in 1857. At the moment, the exact causes of the development of the disease have not been established. There are only a few genes known whose mutation can lead to this disorder. The hereditary nature of the disease and the presence of concomitant chromosomal abnormalities in some patients are also noted. It is important to note that in most patients the disease appears from approximately 3 to 12 years of age in boys and from puberty in girls. The disease occurs either as a result of a mutation in one of the genes