Amyloidosis Indian

Indian amyloid is a hereditary non-infectious systemic disease, which is characterized by disturbances of protein metabolism in organs and tissues. The disease was discovered in the first half of the twentieth century in India, which is why it has a second name - “tanner's disease.”

Indian amyloid occurs rarely and is usually asymptomatic. But at the same time, damage to the nervous and cardiovascular systems is observed, blindness and other complications develop. Most cases of the disease are detected among people from 20 to 50 years old; cases also occur in children, although the disease manifests itself much less frequently in them. The prevalence of the disease is mainly present in cities where the chemical industry is widespread.

The main symptoms are: - uveitis, i.e. inflammation of the retina and iris; - fatty liver (hepatomegaly); - inflammation of the spleen (splenomegaly).

There are two forms of Indian amyloidosis. The early form occurs in patients in childhood and is manifested by disorders

Amyloidosis "Indian" (Indian form) is a hereditary disease from the group of systemic amyloidoses. The disease is characterized by the development of hypervascularization of internal organs, which results in damage to parenchymal organs. Hemosiderin in the blood in this case is of a primary nature, and there is pronounced bone marrow hyperplasia. A distinctive feature of this form of amyloidosis, in contrast to other forms, is an enlargement of the spleen, liver, and diaphragm, and the enlargement of these organs can occur relatively slowly.