Economo-Fisher Syndrome

Economy-Fisher syndrome is a rare hereditary disease that manifests itself in the form of hearing and vision loss in children at an early age. The syndrome is named after the Austrian neurologists Karl Economo and Otto Fischer, who described it in 1913.

Economy-Fisher syndrome is associated with a mutation in the SLC26A4 gene, which encodes a protein needed to transmit signals from cells in the retina and inner ear to the brain. This mutation leads to disruption of the transmission of these signals, which in turn causes loss of vision and hearing.

Symptoms of Economy Fisher syndrome usually appear during the first two years of a child's life. Children with this syndrome may have problems with speech, hearing and vision, as well as problems with motor coordination and balance.

Treatment for Economy-Fisher syndrome includes auditory and visual rehabilitation, as well as drug therapy to improve nerve signal transmission. However, since the syndrome is hereditary, treatment can only be symptomatic and not eliminate the underlying cause of the disease.

Economo-Fisher syndrome is a mysterious disease in which there is muscle paralysis affecting the upper extremities and ganglionopathy (a disease of the peripheral nervous system) develops. The phenomenon was first described in 1906 by a group of Italian scientists who suggested the presence of a unique syndrome