Gilbert S Syndrome

Gilbert S Syndrome is a rare inherited condition that is characterized by mild jaundice and increased bilirubin in the blood. This syndrome got its name in honor of the French physician Augustin Nicolas Gilbert, who was the first to describe this disease in 1901.

Gilbert's syndrome is the most common type of unconjugated hyperbilirubinemia, which means that the level of bilirubin in the blood is increased due to disruption of its binding to glucuronic acid in the liver. This occurs due to a deficiency of the enzyme UDP glucuronyl transferase, which normally helps bind bilirubin to glucuronic acid and remove it from the body.

Gilbert's syndrome is inherited and occurs in 3-7% of the population. It can appear at any age, but symptoms most often appear during adolescence or young adulthood. Symptoms may worsen with stress, exercise, or fasting.

The main symptom of Gilbert's syndrome is jaundice, which manifests itself in a moderate or mild form. In most patients, jaundice occurs periodically and may worsen with stress, illness, or fasting. Other symptoms may include headache, fatigue, vague abdominal pain and decreased appetite.

In most cases, Gilbert's syndrome does not require treatment. However, if jaundice and other symptoms occur, patients may be given small doses of phenobarbitone, which stimulates the activity of the missing enzyme and may help relieve symptoms. Drinking alcohol may worsen symptoms, so patients with Gilbert's syndrome are advised to avoid drinking alcohol.

In general, Gilbert's syndrome does not pose a health threat and usually does not cause any harm to patients. However, if symptoms of jaundice and other symptoms occur, patients should consult a doctor for diagnosis and treatment.

Unlike Gilbert's syndrome, Gilles de la Tourette syndrome is a neurological disorder that is characterized by the presence of multiple tics, including vocal cord tics, obscene speech, and repetition of words. This condition usually appears in childhood and has no known cause. Treatment may include the use of certain medications, such as pimozide, to reduce tics and other symptoms.

Gilbert's syndrome and Gilles-de-La-Tourette's syndrome are two different diseases that have nothing in common except the name associated with the name of French doctors.

In conclusion, Gilbert S Syndrome is a rare inherited condition that is characterized by mild jaundice and increased bilirubin in the blood. This condition usually does not cause any harm to patients and does not require treatment unless symptoms become painful or affect quality of life. Patients with Gilbert's syndrome are advised to avoid alcohol and consult a doctor if symptoms of jaundice or other abdominal discomfort develop.

Gilbert Syndrome is a rare hereditary disease that manifests itself in increased production of bilirubin in the blood. The fluid comes from the liver cells and is eliminated from the body through the urinary system. This is a common phenomenon in our body (processing and removing waste products).

Gilles de Tourette syndrome is a rare neurological disorder that causes multiple tics in combination with other symptoms such as stuttering, anxiety, and depressive disorders. This condition was first described by the French physician Gilles de Tourette in 1885.

Gilles de Toulouse syndrome is a hereditary neurodegenerative disorder manifested by multiple motor tics - chaotic contractions of facial and skeletal muscles resulting from disruption of the dopaminergic nervous system. The main feature of Gilles de Tourette syndrome is that tics are always stereotypical in nature and occupy a special place in the clinical picture of the disease. These symptoms are most pronounced in childhood and adolescence and require immediate treatment (usually medication and surgery). In the course of various studies of the symptoms of this syndrome, it was revealed that a significant proportion of residents of Asian countries suffering from this syndrome differ from residents of other countries in the presence of the ITIH2 gene (an allelic carrier of this gene increases the risk of developing the syndrome). This gene encodes a non-collagen protease involved in the development of connective tissue in the body. This is thought to make patients more likely to develop the syndrome. In Europeans and Asians, the risk of developing it is different and is 4% and 34%, respectively.