Guildford Syndrome

Of course, here's an article about Guilford syndrome. Here's a description of how it develops:

**Gilford syndrome** (GS) is a hereditary disease that manifests itself at birth with microcephaly and a rapid progressive course. By the first year of life it reaches its maximum degree. Children suffer mind



**Gilford (n. Gilford; sin. Garthing's prageria, Gerodermi diurna, Goetching's protеуia) syndrome** is a rare hereditary autosomal recessive disease manifested by elongation of the spine with signs of gerontology in childhood; chronic arthritis and muscle hypotonia. As patients age, herniated cervical discs develop, leading to paralysis. The hereditary disease Guilford syndrome is the cause of gerontological syndrome at a very young age of patients. Patients with Guilfordi syndrome are characterized by the development of bilateral cerebral atherosclerosis, sclerosis and destructive changes in brain synapses with premature development of symptoms of degeneration. This syndrome is inherited as an autosomal recessive type (autosomal 4). The patient has an increased level of excretion of unsaturated fatty acids from the body. The risk of developing tumor diseases of the musculoskeletal system is increased.

Patients suffering from the pathology are phenotypically identical to each other, but the manifestations of the syndrome may vary. The main symptoms of the disease include the following: excessive growth; the presence of atrophic arthritis; progressive muscle hypotonia; senile changes in the nature of the skin and mucous membranes. There is a deformation of the chest and a narrow pelvis. Such hereditary diseases always appear in early childhood or even infancy. Over time, the symptoms of Guildford disease become more pronounced. Deformation of the chest and pelvis progresses, and the cervical spine grows. The child's neck and torso lengthen. Nasal cartilage in children with similar inheritance