Thrombocytopathy Hemorrhagic

**Thrombocytopenia of the hemorrhagic type** is a group of rare genetic coagulation disorders that occur with an almost normal number of cells and low properties of adhesion, aggregation and their life cycle.

According to the new classification, thrombocytopenia is divided into five types: essential, accompanying thrombosis

Thrombophilia, leukocytosis in chronic infection, bleeding; a decrease in the number of platelets significantly reduces blood clotting up to the development of hemorrhage (bleeding). The diagnosis of hemorrhagic THROMBOCYTOPATHY is established based on the nature of bleeding. The diagnosis is also confirmed by a history of hemarthrosis, hemorrhages in the joints and skin.

In THROMBOCYTOPLASTIC DIATHESIS, EDEMA, hyperpigmentation, and signs of thrombocytopenia are absent. A decrease in the number of platelets is observed in the periphery, mainly in juveniles. To diagnose thrombocytosis, it is necessary to determine the thrombin clotting time. Specifically for diathesis, antibodies to the glycoprotein gp 11b/IX (designated GPIb-120 in the international immunological abbreviation) are used. In children, hyper- or hypogammaglobulinemia occurs (increased or decreased concentration of g-globulin fraction antibodies in the blood). When making a diagnosis, concomitant pathology is taken into account (in case of neuromegaly, the level of gonadotropin is determined, in case of adrenal insufficiency - adrenaline, norepinephrine and cortisol).

Literature:

* Directory “Medicine” * A.L.